Drug Information
| Drug Generic Name | EPIRUBICIN HYDROCHLORIDE |
| Drug Class | CYTOTOXIC ANTIBIOTICS |
| Chapter | Malignant Disease & Immunosuppression |
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This is an anthracycline antibiotic with antineoplastic actions similar to those of doxorubicin (structurally – related to doxorubicin). Indications: acute leukaemias, lymphomas, multiple myeloma, solid tumours including cancer of bladder, breast, cervix and gastrointestinal tract. Cautions: reduce dose in hepatic impairment; irritant to tissues. Contra-indications: pregnancy & breast feeding Side effect: cardiotoxcity and myelotoxicity is more likely when the cumulative dose exceeds 0.9 to 1 g per m2 body-surface. |
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