This is an antimuscarinic drug.

Indications: Parkinsonism, particularly with apathy and depression; drug-induced extrapyramidal symptoms (but not tardive dyskinesia).

Cautions: same as for Benzhexol Hydrochloride.

Contra-indications: gastrointestinal obstruction; tardive dyskinesia; also porphyria.

Side Effects: same as for Benzhexol Hydrochloride, less commonly insomnia and impaired coordination.

Dose: initially 150 mg daily in divided doses, increased gradually in steps of 50 mg every 2–3 days according to response; usual dose range 150–300 mg daily in divided doses; max. 400 mg daily; ELDERLY preferably lower end of range.